Immune Strategy
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= A different way to look at the battle against cancer = | = A different way to look at the battle against cancer = | ||
| - | + | We are waging a battle against cancer where the focus is on killing the cancer. Maybe there is a better solution to the problem. Perhaps the focus should be on training the ummune system to kill the cancer rather than trying to kill the cancer directly. | |
| - | Perhaps the idea of killing the cancer directly is flawed. Perhaps the goal should be focused on training the immune system to kill the cancer and focus on educating the immune system and not killing the cancer as the immediate goal. | + | == Killing cancer might not be the best idea == |
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| + | The normal way to fight cancer has been to attack the cancer to kill it as hard as possible. When cancer returns you try to kill it again with something else, and then repeat to patient dies of either the cancer of the side effects of the treatment. A;though this can by some time, when it comes to the fatal cancers the cancer always wins in the long run. | ||
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| + | Perhaps the idea of killing the cancer directly is a flawed idea. It's easy to get in the traditional mindset that focuses on the killing to the exclusion of other paradigms. | ||
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| + | Perhaps the goal should be focused on training the immune system to kill the cancer and focus on educating the immune system and not killing the cancer as the immediate goal. | ||
In order for the immune system to learn cancer you need to: | In order for the immune system to learn cancer you need to: | ||
Revision as of 21:00, 3 November 2016
A different way to look at the battle against cancer
We are waging a battle against cancer where the focus is on killing the cancer. Maybe there is a better solution to the problem. Perhaps the focus should be on training the ummune system to kill the cancer rather than trying to kill the cancer directly.
Killing cancer might not be the best idea
The normal way to fight cancer has been to attack the cancer to kill it as hard as possible. When cancer returns you try to kill it again with something else, and then repeat to patient dies of either the cancer of the side effects of the treatment. A;though this can by some time, when it comes to the fatal cancers the cancer always wins in the long run.
Perhaps the idea of killing the cancer directly is a flawed idea. It's easy to get in the traditional mindset that focuses on the killing to the exclusion of other paradigms.
Perhaps the goal should be focused on training the immune system to kill the cancer and focus on educating the immune system and not killing the cancer as the immediate goal.
In order for the immune system to learn cancer you need to:
1) Kill / wound enough cancer to allow the "smell" of the cancer to be out there for the adaptive immune system learn from. This is accomplished by:
a) Targeted kainase inhibitors (Caprelsa) at lower dosages to kill / wound cancer more slowly and reduce side effects.
b) Use mTor inhibitor combination to make targeted inhibitors more effective in low dosages.
c) Combination of
b) Radiation in low dosages - not to try to kill the tumor - but to kill / wound enough to create the smell of dying cancer.
2) Use combination of a low dose of Opdivo and Yervoy (Checkpoint inhibitors) to unmask the cancer
